Jumat, 31 Januari 2014

[Y807.Ebook] Ebook Lateral Flow ImmunoassayFrom Brand: Humana Press

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Due to the simplicity, relative accuracy, fast result reporting, and user-friendliness of lateral flow immunoassay, its use has undergone tremendous growth in the diagnostic industry in the last few years. Such technology has been utilized widely and includes pregnancy and woman's health determination, cardiac and emergency conditions monitoring and testing, infectious disease including Flu screening, cancer marker screening, and drugs abuse testing. This book covers the scope of utilization, the principle of the technology, the patent concerns, information on the development and production of the test device and specific applications will be of interest to the diagnostic industry and the general scientific community.

  • Sales Rank: #2554170 in Books
  • Brand: Brand: Humana Press
  • Published on: 2008-12-15
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.21" h x .56" w x 6.14" l, 1.00 pounds
  • Binding: Hardcover
  • 224 pages
Features
  • Used Book in Good Condition

From the Back Cover

Due to the simplicity, relative accuracy, fast result reporting, and user-friendliness of lateral flow immunoassay, its use has undergone tremendous growth in the diagnostic industry in the last few years. Such technology has been utilized widely and includes: pregnancy and woman's health determination, cardiac and emergency conditions monitoring and testing, infectious disease including Flu screening, cancer marker screening, and drugs abuse testing. Lateral Flow Immunoassay covers the scope of utilization, the principle of the technology, the patent concerns, information on the development and production of the test device and specific applications will be of interest to the diagnostic industry and the gereal scientific community.

Most helpful customer reviews

1 of 13 people found the following review helpful.
Could Hardly put it Down!!
By Sam Grouper
Oh man, this book will keep you at the edge of your seat. The author is a real "word smith" if you know what I'm saying.

0 of 0 people found the following review helpful.
A superb overview of LFIA technology
By Bohdan Shmorhay
Those seeking to beat drug tests will be disappointed by this book. For drug-war chemical "arms race" information, look elsewhere, such as online websites or hardcopy publications in head shops. But for anyone designing, building, or using Lateral Flow Immunoassay (LFIA) medical devices (test strips) in R&D, manufacturing, or clinical settings, this is a mandatory textbook, and a very, very good one.

The price is steep--ten times that of a typical non-fiction 200-page trade paperback. Is it worth it? A resounding Yes! The construction, chemistry, and manufacturing of LFIA devices are all covered in depth. LFIA-based products are used to test for hundreds of metabolic and infectious disease indicators, both in the field and at home. This book ensures you will be deeply and well-informed about LFIA testing strengths and weaknesses.

Some caveats--this book is not light reading for the beach. While most sentences are finely polished gems, you will need to plow through this book methodically, as you would a math or a programming book. Different aspects of LFIA are discussed from different perspectives, and the full picture emerges only slowly, but will be exciting and rewarding to those who persist--there is much to know about such seemingly trivial technology. (The strength of LFIA is its simplicity. So is its weakness.)

So be patient--everything is explained eventually, just not in any one chapter or section. Also, a bit more copyediting to sprinkle some words like "the" here and there would smooth out some syntax. But that is a minor quibble. Overall, if you are in the test strip immunoassay business to monitor the qualitative presence or absence of key indicators in saliva, blood, urine, or food samples, without fielding expensive chromatography or spectrometry equipment, get this book and study it intently. The knowledge payoff will be enormous.

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Rabu, 29 Januari 2014

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Title: The Power of the Pussy( Get What You Want from Men( Love Respect Commitment and More!) Binding: Paperback Author: KaraKing Publisher: Createspace

  • Published on: 2012-06-30
  • Binding: Paperback

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Senin, 27 Januari 2014

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  • Original language: French
  • Dimensions: 6.93" h x .79" w x 10.51" l,
  • Binding: Album

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Sabtu, 25 Januari 2014

[N579.Ebook] Free PDF An Introduction to Design and Analysis of Algorithms, 2/e ( New Edition), by Anany Levitin

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Based on a new classification of algorithm design techniques and a clear delineation of analysis methods, "introduction to the design and analysis of algorithms" presents the subject in a coherent and innovative manner. Written in a student friendly styl

  • Sales Rank: #4455231 in Books
  • Published on: 2009
  • Original language: English
  • Dimensions: .0" h x .0" w x .0" l, 1.15 pounds
  • Binding: Paperback

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Selasa, 21 Januari 2014

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Available to order from June 2015.This is an OPEN ACCESS title.�What is digital business reporting? Why do we need it? And how can we improve it? This book aims to address these questions by illustrating the rise of system-to-system information exchange and the opportunities for improving transparency and accountability. Governments around the world are looking for ways to strengthen transparency and accountability without introducing more red tape, which is a source of growing frustration and costs for businesses.�In 2004, the Ministry of Finance and the Ministry of Justice in the Netherlands started to investigate the potential of XBRL (eXtensible Business Reporting Language) as a uniform data standard for business-to-government information exchange. In 2006, there was a comprehensive architecture for Standard Business Reporting (SBR), including the requirements for the information infrastructure. One year later the first reports in XBRL were successfully delivered to the Tax and Customs Administration and the Chamber of Commerce via a secure infrastructure. Today, millions of business reports are being exchanged using SBR. As a solution, SBR empowers organisations to present a cohesive explanation of their business operations and helps them engage with internal and external stakeholders, including regulators, shareholders and creditors.�Challenging the chain describes the journey of SBR from challenge to solution. Specialists in the field flanked by academics provide detailed insights on the challenges actors faced and the solutions they achieved. In its versatility, this book exemplifies the necessary paradigm shifts when it comes to such large-scale public-private transformations. Policy makers, managers, IT specialists and architects looking to engage in such transformations will find guidance in this book.

  • Published on: 2015-06-15
  • Original language: English
  • Dimensions: 9.25" h x 6.50" w x 1.00" l, 1.80 pounds
  • Binding: Paperback
  • 444 pages

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Jumat, 17 Januari 2014

[J389.Ebook] PDF Ebook Material Christianity: Religion and Popular Culture in America, by Colleen McDannell

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Material Christianity: Religion and Popular Culture in America, by Colleen McDannell

What can the religious objects used by nineteenth- and twentieth-century Americans tell us about American Christianity? What is the relationship between the beliefs of the faithful and the landscapes they build? This lavishly illustrated book investigates the history and meaning of Christian material culture in America over the last 150 years. Drawing on a rich array of historical sources and on in-depth interviews with Protestants, Catholics, and Mormons, Colleen McDannell examines the relationship between religion and mass consumption. McDannell claims that previous studies of American Christianity have overemphasized the written, cognitive, and ethical dimensions of religion, presenting faith as a disembodied system of beliefs. She shifts attention from the church and the theological seminary to the workplace, home, cemetery, and Sunday school. Thus McDannell highlights a different Christianity - one in which average Christians experience the divine, the nature of death, the power of healing, and the meaning of community through interacting with a created world of devotional images, environments, and objects.

  • Sales Rank: #517595 in Books
  • Published on: 1995
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.36" h x .99" w x 7.64" l, 2.28 pounds
  • Binding: Paperback
  • 324 pages

Amazon.com Review
It's tough to be devout and kitschy at the same time, but Colleen McDannell strikes that delicate balance with admirable poise in Material Christianity: Religion and Popular Culture in America. Her book is an argument that "American Christians ... want to see, hear, and touch God. It is not enough for Christians to go to church, lead a righteous life, and hope for an eventual place in heaven." This argument is amply defended by smart essays about family Bibles, gravestone design, and Lourdes Water, as well as hundreds of illustrations of vestments, churches, portraits of Jesus, rapture T-shirts, and backyard statues of Our Lady. Where Material Christianity gets really interesting, however, is in its assertion that "Christian material culture does not simply reflect an existing reality. Experiencing the physical dimension of religion helps bring about religious values, norms, behaviors, and attitudes." For example, the warmth and intimacy of Warner Sallman's painting "Head of Christ," which hung in almost every Protestant Sunday School classroom in America until the 1960s, was probably every bit as influential as any given phrase from the Sermon on the Mount in determining the personal nature of Protestants' relationships with Jesus. Material Christianity covers a lot of ground--from Mormonism to fundamentalism--and every chapter is as theologically wise as it as aesthetically astute. --Michael Joseph Gross

From the Back Cover
What can the religious objects used by nineteenth- and twentieth-century Americans tell us about American Christianity? What is the relationship between the beliefs of the faithful and the landscapes they build? This lavishly illustrated book investigates the history and meaning of Christian material culture in America over the last 150 years. Drawing on a rich array of historical sources and on in-depth interviews with Protestants, Catholics, and Mormons, Colleen McDannell examines the relationship between religion and mass consumption. McDannell claims that previous studies of American Christianity have overemphasized the written, cognitive, and ethical dimensions of religion, presenting faith as a disembodied system of beliefs. She shifts attention from the church and the theological seminary to the workplace, home, cemetery, and Sunday school. Thus McDannell highlights a different Christianity - one in which average Christians experience the divine, the nature of death, the power of healing, and the meaning of community through interacting with a created world of devotional images, environments, and objects.

About the Author
Colleen McDannell is Sterling M. McMurrin Professor of Religious Studies and Professor of History at the University of Utah in Salt Lake City. She is the author of Picturing Faith: Photography and the Great Depression, Material Christianity: Religion and Popular Culture in America and Heaven: A
History.

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Rabu, 15 Januari 2014

[H141.Ebook] Free Ebook Stroke Recovery and Rehabilitation, 2nd EditionFrom Demos Medical

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Stroke Recovery and Rehabilitation, 2nd EditionFrom Demos Medical

The definitive core text in its field, Stroke Recovery and Rehabilitation is a comprehensive reference covering all aspects of stroke rehabilitation � from neurophysiology of stroke through the latest treatments and interventions for functional recovery and restoration of mobility. This second edition is completely updated to reflect recent advances in scientific understanding of neural recovery and growing evidence for new clinical therapies.

The second edition � which includes free e-book access with every print purchase � continues to provide in-depth information on the assessment and management of all acute and long-term stroke-related impairments and complications including cognitive dysfunctions, musculoskeletal pain, and psychological issues.

It examines risk factors, epidemiology, prevention, and neurophysiology as well as complementary and alternative therapies, functional assessments, care systems, ethical issues, and community and psychosocial reintegration.

With contributions from over 100 acknowledged leaders from every branch of the stroke recovery field, this edition features expanded coverage of key issues such as the role of robotics and virtual reality in rehabilitation. New chapters have been incorporated to cover fields of recent exploration including transcranial magnetic stimulation, biomarkers, and genetics of recovery as well as essentials like the use of medication and the survivor�s perspective. The up-to-date presentation of scientific underpinnings and multi-specialty clinical perspectives from physical medicine and rehabilitation, neurology, physical therapy, occupational therapy, speech and language pathology, and nursing ensures that Stroke Recovery and Rehabilitation will continue to serve as an invaluable reference for every health care professional working to restore function and help stroke survivors achieve their maximum potential.

New to Stroke Recovery and Rehabilitation, Second Edition

  • All chapters are thoroughly revised and updated to reflect advances in scientific understanding of neural recovery and clinical progress
  • Five completely new chapters and expanded coverage of key issues that drive the field forward
  • New contributions from leading stroke specialists from all involved disciplines
  • Includes access to the fully-searchable downloadable ebook

  • Sales Rank: #986245 in eBooks
  • Published on: 2014-09-18
  • Released on: 2014-09-18
  • Format: Kindle eBook

About the Author
Simon Baruch Professor of Physical Medicine and Rehabilitation and Chair, Department of Rehabilitation Medicine, Columbia University College of Physicians and Surgeons, Professor and Chief, Division of Rehabilitation Medicine, Weill Cornell Medical College, Physiatrist-in-Chief, Department of Rehabilitation Medicine, New York Presbyterian Hospital, New York, New York.

Associate Professor for the Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine, Wesley and Suzanne Dixon Stroke Chair, Medical Director, Stroke Rehabilitation Program, Rehabilitation Institute of Chicago, Chicago Illinois.

Professor and Director of Research, Division of Biokinesiology and Physical Therapy, University of Southern California School of Dentistry, Los Angeles, California.

Associate Professor, Department of Physical Medicine and Rehabilitation, Johns Hopkins School of Medicine, Chairman, Department of Physical Medicine and Rehabilitation, Johns Hopkins Bayview Medical Center, Baltimore, Maryland.

Associate Professor of Neurology, University of Maryland School of Medicine, Baltimore, Maryland

Most helpful customer reviews

0 of 0 people found the following review helpful.
Treating Strokes
By Charles P. Poole, Jr.
This is the definitive book on the subject. It tells everything any one would want to know about the subject. It tends to utilize highly technical language so it is important to have a good dictionary nearby while reading it. I very highly recommend it to people who either suffer from a stroke, or who treat or who care for stroke victims.

0 of 0 people found the following review helpful.
Amazing book!
By RehabDoc
Perfect for a resident physician in the fields of Neurology, PM&R, and Vascular surgery.

0 of 0 people found the following review helpful.
Five Stars
By Snow White
Excellent

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Selasa, 07 Januari 2014

[P618.Ebook] Download World Ethics, by Wanda Torres-Gregory, Donna Giancola

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World Ethics, by Wanda Torres-Gregory, Donna Giancola

Unique among multicultural-minded introduction to ethics textbooks, WORLD ETHICS is first and foremost an introduction to ethical theory, not to applied ethics. And unique among introduction to ethical theory textbooks, WORLD ETHICS is firmly committed to exploring ethical theories of the World, not just those of the European philosophical mainstream. Consisting of sixty primary source readings from a variety of world philosophical traditions, this text will enable instructors, majors, and non-majors to engage the fundamental questions of ethics amidst a much more diverse array of standpoints than is typically featured in an introduction to ethics textbook. The coverage of the European tradition in this volume alone is richer than most introductory ethics anthologies. Inasmuch as WORLD ETHICS provides not only this traditional coverage, but also equally exceptional treatment of Asian, Feminist, and a number of other contemporary cultural theoretical perspectives, this title is bound to be of landmark and lasting value to the teaching of ethics.

  • Sales Rank: #431316 in Books
  • Brand: Brand: Cengage Learning
  • Published on: 2002-06-14
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.25" h x .94" w x 7.38" l, 1.55 pounds
  • Binding: Paperback
  • 416 pages
Features
  • Used Book in Good Condition

Review
Part I: THE EUROPEAN TRADITIONS. 1. Socrates. Selections from Plato's EUTHYPHRO. 2. Plato. Selections from REPUBLIC, Books I, II, IV, VI, VII, IX. 3. Aristotle. Selections from NICOMACHEAN ETHICS, Books I, II, IX. 4. Epicurus. "Letter to Menoceus". 5. Epictetus. Selections from THE DISCOURSES. 6. Augustine. Selections from CITY OF GOD, Books XII and XIX. 7. Moses Maimonides. Selections from GUIDE FOR THE PERPLEXED, Part 1, Chapter 2. 8. Thomas Aquinas. Selections from SUMMA THEOLOGICA, Volume 2, Part I. 9. David Hume. Selections from AN ENQUIRY CONCERNING THE PRINCIPLES OF MORALS, Sections I, II, III and V. 10. Immanuel Kant. Selections from FUNDAMENTAL PRINCIPLES OF THE METAPHYSIC OF MORALS, Sections 1 and 2. 11. John Stuart Mill. Selections from "What Utilitarianism is". 12. SOren Kierkegaard. Selections from EITHER/OR. Selections from FEAR AND TREMBLING. 13. Karl Marx. Selections from ECONOMIC AND PHILOSOPHICAL MANUSCRIPTS, First and Third Manuscripts. 14. Friedrich Nietzsche. Selections from "What is Noble?" 15. G.E. Moore. Selections from "The Subject-Matter of Ethics". 16. Martin Buber. Selections from I AND THOU, First, Second, and Third Parts. 17. Ruth Benedict. Selections from "Anthropology and the Abnormal". 18. A.J. Ayer. Selections from "Critique of Ethics and Theology". 19. Jean Paul Sartre. Selections from EXISTENTIALISM AND HUMAN EMOTIONS. 20. Ayn Rand. Selections from THE VIRTUE OF SELFISHNESS. 21. John Rawls. Selections from A THEORY OF JUSTICE. 22. Emmanuel Levinas. Selections from "The Face" and "Responsibility for the Other". 23. Alasdair McIntyre. Selections from "The Virtues, the Unity of a Human Life and the Concept of a Tradition". Part II: THE ASIAN TRADITIONS. 24. Lao Tzu. Selections from TAO TEH CHING. 25. The Bhagavad Gita. Selections from the BHAGAVAD GITA, Chapters 2, 3, 4, 5, and 18. 26. The Buddha. Selections from "The First Sermon" and "Synopsis of Truth". 27. Confucius. Selections from the ANALECTS, Books I, II, IV, VII, VIII, XII, XIV, XV, and XX. 28. Mencius. Selections from THE BOOK OF MENCIUS. 29. Hsun Tzu. Selections from "The Nature of Man is Evil". 30. The Dhammapada. Selections from the DHAMMAPADA. 31. Santideva. Selections from the BODHICARYAVATARA, Chapters 1, 3, 8, and 10. 32. Al-Ghazali. "The Ways of Mysticism". 33. Mohandas Gandhi. Selections from GANDHI ON NON-VIOLENCE, Sections 1 and 2. 34. Thich Nhat Hanh. Selections from "The Sun in My Heart". Part III: CONTEMPORARY CULTURAL PERSPECTIVES. 35. Kwame Nkrumah. Selections from "Consciencism". 36. Leopold Sedar Senghor. Selections from "Negritude: A Humanism of the Twentieth Century". 37. Paul Mbuya Akoko. Selections from Henry Odera Oruka's SAGE PHILOSOPHY. 38. Oruka Rang'inya. Selections from Henry Odera Oruka's SAGE PHILOSOPHY. 39. W.E.B. Du Bois. Selections from "The Development of a People". 40. Martin Luther King, Jr. Selections from "Letter from a Birmingham Jail". 41. Malcolm X. Selections from "The Black Revolution". 42. Angela Davis. Selections from "Radical Perspectives on Empowerment for Afro-American Women: Lessons for the 1980s". 43. Cornel West. Selections from "The Pitfalls of Racial Reasoning". 44. Aime Cesaire. Selections from "Discourse on Colonialism". 45. Frantz Fanon. Selections from "Racism and Culture". 46. Paulo Freire. Selections from PEDAGOGY OF THE OPPRESSED. 47. Enrique Dussel. Selections from "Prevailing Social Morality: The Babylon Principle". 48. Black Elk. "The Offering of the Pipe". Part IV: CONTEMPORARY FEMINIST PHILOSOPHERS. 49. Simone de Beauvoir. Selections from THE SECOND SEX, "Introduction". 50. Carol Gilligan. Selections from "In a Different Voice: Women's Conceptions of Self and of Morality". 51. Mary Daly. Selections from "The Metapatriarchal Journey of Exorcism and Ecstasy". 52. Luce Irigaray. Selections from "An Ethics of Sexual Difference". 53. Maria Lugones and Elizabeth Spelman. Selections from "Have We Got a Theory for You!: Feminist Theory, Cultural Imperialism, and the Demand for a 'Woman's Voice'". 54. Nel Noddings. Selections from CARING: A FEMININE APPROACH TO ETHICS AND MORAL EDUCATION, "Introduction". 55. Annette Baier. Selections from "What Do Women Want in a Moral Theory?" 56. Bell Hooks. Selections from "Feminism: A Transformational Politic". 57. Alison Jaggar. Selections from "Feminist Ethics: Projects, Problems, Prospects". 58. Sarah Lucia Hoagland. Selections from "Why Lesbian Ethics?". 59. Sara Ruddick. Selections from "From Maternal Thinking to Peace Politics". 60. Rosemary Radford Ruether. Selections from "Ecofeminism: Symbolic and Social Connections of the Oppression of Women and the Domination of Nature".

Most helpful customer reviews

10 of 11 people found the following review helpful.
You do not get what you pay for
By Robin Son
At least not for this text. I've only been using this text for three weeks now, but thus far, I don't hold it in very high regard. For 60 dollars, I would expect much fuller and more thorough content. Neither Aristotle's nor Plato's function argument are included in the readings. Socrates' initial objections to Thrasymachus and Glaucon are completely omitted, in favor of a description of the theory of the forms. The forms are presumably mentioned as they are relevant to the allegory of the cave, but the relationship between the Philosopher Kings and the prisoners in the cave is never made clear. Instead, Socrates' entire argument is contained in his brief discussion of the three bodied monster.

Mill's argument for the greatest happiness principle is omitted. Students are left to wonder what is the relationship between happiness, pleasure, and (most importantly) the good. Mill makes the point clear, but from this reading, we're left wondering.

I suspect that most of these issues could be resolved in a future edition. I think the range of choices available here is commendable, but of course no undergraduate course in ethics could ever complete even a fourth of it. Although it concentrates on ethical theory, a book entitled 'World Ethics' could stand a small section on applied topics as well.

Any instructor who chooses this book will find him/herself making extra copies of a page or two of text for every reading. I would instead suggest Cahn and Sterba's 'Exploring Ethics' or Singer's 'Blackwell Companion to Ethics'. The latter is a better value, even given it's age, and the former is more expensive, but not dramatically so, with much added content.

I like the study questions, and the suggested readings sections. They are very thorough.

0 of 0 people found the following review helpful.
Five Stars
By Diane
The book was just as it was described and was received before the time frame quoted.

0 of 0 people found the following review helpful.
One Star
By AzureNoir
Unfortunately got fooled with the title and content

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Rabu, 01 Januari 2014

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This Close to Happy: A Reckoning with Depression, by Daphne Merkin

A New York Times Book Review Favorite Read of 2016

“Despair is always described as dull,” writes Daphne Merkin, “when the truth is that despair has a light all its own, a lunar glow, the color of mottled silver.” This Close to Happy―Merkin’s rare, vividly personal account of what it feels like to suffer from clinical depression―captures this strange light.

Daphne Merkin has been hospitalized three times: first, in grade school, for childhood depression; years later, after her daughter was born, for severe postpartum depression; and later still, after her mother died, for obsessive suicidal thinking. Recounting this series of hospitalizations, as well as her visits to myriad therapists and psychopharmacologists, Merkin fearlessly offers what the child psychiatrist Harold Koplewicz calls “the inside view of navigating a chronic psychiatric illness to a realistic outcome.” The arc of Merkin’s affliction is lifelong, beginning in a childhood largely bereft of love and stretching into the present, where Merkin lives a high-functioning life and her depression is manageable, if not “cured.” “The opposite of depression,” she writes with characteristic insight, “is not a state of unimaginable happiness . . . but a state of relative all-right-ness.”

In this dark yet vital memoir, Merkin describes not only the harrowing sorrow that she has known all her life, but also her early, redemptive love of reading and gradual emergence as a writer. Written with an acute understanding of the ways in which her condition has evolved as well as affected those around her, This Close to Happy is an utterly candid coming-to-terms with an illness that many share but few talk about, one that remains shrouded in stigma. In the words of the distinguished psychologist Carol Gilligan, “It brings a stunningly perceptive voice into the forefront of the conversation about depression, one that is both reassuring and revelatory.”

  • Sales Rank: #10930 in Books
  • Brand: Farrar Straus and Giroux
  • Published on: 2017-02-07
  • Released on: 2017-02-07
  • Original language: English
  • Number of items: 1
  • Dimensions: 8.52" h x .4" w x 5.85" l, .0 pounds
  • Binding: Hardcover
  • 304 pages
Features
  • Farrar Straus and Giroux

Review

"[Merkin narrates] with insight, grace and excruciating clarity, in exquisite and sometimes darkly humorous prose . . . For all its highly personal focus, [This Close to Happy] is an important addition to the literature of mental illness." ―Andrew Solomon, The New York Times Book Review (cover review)

"I will not be the last to thank Ms. Merkin for resisting this desire [to die] long enough to give us what is one of the most accurate, and therefore most harrowing, accounts of depression to be written in the last century . . . Ms. Merkin speaks candidly and beautifully about aspects of the human condition that usually remain pointedly silent." ―John Kaag, Wall Street Journal

"Wry, self-aware . . . a work of lacerating intelligence about a condition that intellect cannot heal." ―The New Yorker

"[A] triumph on many levels . . . As insightful and beautifully written as it is brave . . . This Close to Happy earns a place among the canon of books on depression . . . books that offer comfort to fellow depressives and elucidation for those lucky enough to have dodged its scourge." ―Heller McAlpin, Washington Post

"[A] stunning self portrait" ―Christian Lorentzen, New York

“A hybrid of memoir, case study, and confession, which joins such classics as Kay Redfield Jamison’s An Unquiet Mind and Andrew Solomon’s The Noonday Demon in the contemporary literature of depression. . . Merkin has written [a book] that will illuminate, challenge, and possibly even console.” ―Adam Kirsch, Tablet

"[This Close to Happy is] a testament to Merkin's commitment to capturing the grim distortions that depression can produce. . . This Close to Happy is more than a memoir of mental illness. Merkin is a good writer―perceptive, provocative, relentlessly interrogative of her own experience―and despite her difficult subject matter, she does, in this memoir, what good writers do: she sends urgent, cogent dispatches from another world, a protracted battlefield that we might not otherwise know about." ―Lisa Fetchko, Los Angeles Review of Books

"[A] compelling chronicle . . . Merkin's work is unique in describing the mundane burden of a deeply felt and closely observed life lived with depression . . . [H]er account of depression is both personal, literary and, at the same time, existential." ―Tom Teicholz, Forbes

“Merkin is a wonderful writer whose keen eye for detail and human foibles enables her to brilliantly light her subject, which is as much her as it is depression. In page after page, she delivers elegant, evocative prose.” ―Psychology Today

"This Close to Happy is as illuminating and hard to put down as it is painful." ―People

"Merkin is a fine stylist . . . She has at her disposal wide-ranging allusions, and she draws on poetry with a charming ease, a frankness that assumes her reader’s sophistication, even as she capably holds the reader’s hand and clarifies the relevance of a particular reference.” ―Forward

"Daphne Merkin exhibits shocking honesty in allowing readers to look into her journey. . . Her depth of writing experience on the topic comes through in emotion-packed prose . . . This book offers the education necessary for readers need to follow depression as it rises and falls in one woman’s life, as well as in the lives of thousands of others." ―Wyatt Massey, America Magazine

“Merkin’s deeply intimate account of living with clinical depression is illuminating, heartbreaking, and powerfully written. With lively prose and shrewd observations . . . Merkin’s exploration into her complicated yet unconditional devotion to her mother is rendered with compassion and profound perception. Merkin eloquently blends the personal with the researched; her intellectual tenacity and emotional rawness impress as much as they entertain. This book is a wonderful addition to literature about the unrelenting battle against depression.” ―Publishers Weekly (starred review)

“Dark thoughts hover over virtually every page of this mesmerizing memoir, and yet there is also the very real possibility of hope. . . Merkin’s exceptional book belongs on the same shelf as such classics as William Styron’s Darkness Visible (1990) and Kay Redfield Jamison’s An Unquiet Mind (1995).” ―Booklist (starred review)

“[Merkin] has a signature method to her writing, one that exuberantly crosshatches high- and lowbrow, and one that reveals and protects in equal measure.” ―Bookforum

“Opening This Close to Happy was like getting a long letter from my best friend at sleepaway camp. I had no idea it was this bad for you, was my first thought, and then, we have both been so paralyzed by grief. This is why we all feel so lonely right now―the longing, the depression, the comedy of it all, wrapped up in a story about sex and Judaism, our mothers. I felt so whole when snuggling up alone with Merkin’s brilliant, full-of-feeling masterpiece. I flew through it and hated to let go when it ended.” ―Jill Soloway

“Fierce, clear-eyed, and beautifully honest, Daphne Merkin’s is an essential voice. This Close to Happy, a lucid and elegantly written account of her lifelong struggles withdepression, unsettles and illuminates in equal measure. This is an important book.” ―Claire Messud

“If the face presented to the world is a mask to protect ourselves, Daphne Merkin bravely removes hers, revealing the truth of herself, courageously exploring, seeking―and sometimes even finding―the hope that glimmers at the end of the tunnel. Please read as soon as possible.” ―Gloria Vanderbilt

“This beautifully written tale of Daphne Merkin’s depressive demons is by far the most accurate and human account of depression and its impact that I have ever read. I highly recommend it, both to those in the mental health professions and to those who care about the suffering of their loved ones.” ―Glen O. Gabbard, M.D.

“The greatness of this book is in the way Merkin takes the measure of the adversary.” ―Peter Sacks

“D. W. Winnicott wrote that depression is the fog over the battlefield. In this extraordinarily lucid and moving book, Daphne Merkin illuminates the dark and desperate battle that depression can be. This is a book for all those who know nothing about depression and for those who know too much.” ―Adam Phillips

“This Close to Happy belongs on the shelf with William Styron's Darkness, Visible and Andrew Solomon's The Noonday Demon. It brings a stunningly perceptive voice to the forefront of the conversation about depression, one that is both reassuring and revelatory.” ―Carol Gilligan, author of In a Different Voice

"This Close to Happy is honest, fearless in the way we have come to expect from Daphne Merkin, and, as a bonus, frankly informative. From Merkin we get the inside view of navigating a chronic psychiatric illness to a realistic outcome. As she writes, 'the opposite of depression is not a state of unimaginable happiness, but a state of relative all-right-ness.' For some, that insight alone will speak volumes. Her candor discussing the fears, tribulations, and triumphs of a lifetime of treatment will be valuable for anyone who loves someone with depression but makes necessary reading for the mental health professionals on the other side of the couch." ―Harold S. Koplewicz, M.D., President, Child Mind Institute

About the Author
Daphne Merkin is a former staff writer for The New Yorker and a regular contributor to Elle. Her writing frequently appears in The New York Times, Bookforum, Departures, Travel + Leisure, W, Vogue, Tablet Magazine, and other publications. Merkin has taught writing at the 92nd Street Y, Marymount College, and Hunter College. Her previous books include Enchantment, which won the Edward Lewis Wallant Award for best novel on a Jewish theme, and two collections of essays, Dreaming of Hitler and The Fame Lunches, which was a New York Times Notable Book of the Year. She lives in New York City.

Most helpful customer reviews

22 of 22 people found the following review helpful.
Depression Unmasked
By Susan M. Baumann
Brilliant, scathing, heartbreaking and raw. This is the most powerfully honest book on depression and child abuse that I have ever read. Merkin's bereft childhood of brutality and lack seems to be the fertile ground that created her despondency and the tenacious, pervasive longing for suicide. Her parents appear blatantly psychologically disordered, meting out damage as casually as one would order lunch. Merkin is by turns, attached to, and repelled by, a vicious mother, who seems both stunningly narcissistic and psychopathic. I was frustrated by Merkin's struggle to detach from her mother, much in the same way that abused wives return to their abusers, expecting different outcomes. Merkin was drowning in depression, yet repeatedly returned to her parents seeking solace, approval and a revisionist history that neither parent was emotionally equipped to provide. The repeated returns to the abusive environment only seemed to exacerbate the depression and parental control, all in a continuous self-perpetuating loop. I rooted for Merkin to cut the toxic ties in favor of mental health and self actualization, but her journey to contentment was more curcuitous. I applaud Merkin's ability to craft riveting and beautiful prose from the wreckage and horror of her early years. This book is both difficult to read at times, and equally hard to put down. My hope is that Merkin never chooses to succumb to the lure of suicide, but instead continues to write, to enjoy simple pleasures and allows herself to heal. A highly recommended read.

15 of 16 people found the following review helpful.
I really disliked this book.
By Nancy J.
I found that reading this book made me more depressed than anything I have ever read. The chapters were quite similar in descriptions of her sad depression and childhood, over and over again. I could not find anything helpful or hopeful in this book. Finally, I skipped to the very last chapter to see if it ended with success, but no, nothing was solved, she was still sad. If you are suffering from clinical depression, this will make you feel worse.

5 of 5 people found the following review helpful.
Insightful, helpful firsthand account of depression
By Rose
I read this while severely depressed and found it helpful. This isn't the point of the book—it's a beautifully-written, insightful, firsthand account of someone's lifelong struggle with depression—but as I imagine a large number of people who pick up this book will, like me, be looking for some insight into their own situation, I'll say that I, for one, found some. I, like Daphne, sometimes struggle to accept depression as an illness as opposed to a personal failing, even as I live it, and reading someone else's honest account—experiencing empathy and finding many shared experiences along the way—encouraged me to be a bit kinder to myself.

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